Publications - Han's Laboratory at KAIST

Kim, T.; Jeon, S.; Jang, Y.; Gotina, L.; Won, J.; Ju, Y.; Kim, S.; Jang, M.; Won, W.; Park, M.; Pae, A.; Han, S.; Kim, S.;* Lee, C. J.* "Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion" submitted (bioRxiv).
Kang, G.; Park, S.; Han, S.* "The Chemistry of High-Oxidation State Securinega Alkaloids" Eur. J. Org. Chem. 2021, in press (YourJOC talents special issue).
Kang, G.; Baik, M.-H.;* Han, S.* "Calculation-Assisted Stereochemical Analysis of Securingine A" Bull. Kor. Chem. Soc. 2021, ASAP (BKCS special issue "Chemical Synthesis & Reaction Development").
Jeon, S.; Lee, J.; Park, S.; Han, S.* "Total Synthesis of Dimeric Securinega Alkaloids (–)-Flueggenines D and I" Chem. Sci. 2020, 11, 10928 (selected as ChemSci Pick of the Week and inside back cover).
Jang, Y.; Han, S.* "Total Synthesis of Cinnamodial-Based Dimer (–)-Capsicodendrin" J. Org. Chem. 2020, 85, 7576.
Kim, G.; Kim. T.; Han, S.* "Total Synthesis of (+)-Pestalofone A and (+)-Iso-A82775C" J. Org. Chem. 2020, 85, 6815.
Lee, S.;^† Kang, G.;^† Chung, G.; Kim, D.; Lee, H.-Y.;* Han, S.* "Biosynthetically Inspired Syntheses of Secu'amamine A and Fluvirosaones A and B" Angew. Chem. Int. Ed. 2020, 59, 6894 (^†These authors contributed equally).
Seong, S.; Lim, H.; Han, S.* "Synthesis of Types II and III Post-Iboga Alkaloids" Strategies and Tactics in Organic Synthesis; Harmata, M., Ed.; Elsevier; 2019, 14, chapter 2, pp 35-59.
Jo, D.; Han, S.* "Total Synthesis of (–)-FD-838 and (–)-Cephalimysin A" Org. Lett. 2019, 21, 6045.
Lim, H.; Seong, S.; Han, S.* "Syntheses of Post-Iboga Alkaloids" Synthesis 2019, 51, 2737 (Bürgenstock Special Section 2018 Future Stars in Organic Chemistry Issue).
Park, J.; Jeon, S.; Kang, G.; Lee, J.; Baik, M.-H.*; Han, S.* "Dimerization Strategies for the Synthesis of High-Order Securinega Alkaloids" J. Org. Chem. 2019, 84, 1398.

Seong, S.;^† Lim, H.;^† Han, S.* "Biosynthetically Inspired Transformation of Iboga to Monomeric Post-Iboga Alkaloids" Chem 2019, 5, 353 (^†These authors contributed equally).
Hwang, J.;^† Kang, T.;^†Lee, J.; Choi, B.-S.;* Han, S.* "Design, Synthesis, and Biological Evaluation of C7-Functionalized DMXAA Derivatives as Potential Human-STING Agonists" Org. Biomol. Chem. 2019, 17, 1869. (^†These authors contributed equally, New Talent 2018 Issue).
Kim, G.; Kim, M. J.; Chung, G.; Lee, H.-Y.;* Han, S.* "(+)-Dimericbiscognienyne A: Total Synthesis and Mechanistic Investigations of the Key Heterodimerization" Org. Lett. 2018, 20, 6886.
Jo, D.; Han, S.* "Total Syntheses of Spirocyclic PKS-NRPS-based Fungal Metabolites" Chem. Comm. 2018, 54, 6750 (Emerging Investigators 2018 Issue).

Kim, T. T.; Kim, H.; Han, S.* "Academic Research Inspired Design of an Expository Organic Chemistry Lab Course." J. Kor. Chem. Soc. 2018, 62, 99 (front cover).
Jeon, S.; Park, J.; Han, S.* "Syntheses of Dimeric Securinega Alkaloids." Synlett 2017, 28, 2353 (Invited Synpacts article).

Kang, T.; Jo, D.; Han, S.* "Six-Step Total Synthesis of Azaspirene." J. Org. Chem. 2017, 82, 9335.
Jeon, S.; Han, S.* "An Accelerated Intermolecular Rauhut–Currier Reaction Enables the Total Synthesis of (–)-Flueggenine C." J. Am. Chem. Soc. 2017, 139, 6302 (highlighted in Synfacts).

Jo, D.; Han, S.* “Biomimetic Total Synthesis of (±)-Berkeleyamide D.” Org. Chem. Front. 2017, 4, 506.
Han, S.; Le, B. V.; Hajare, H. S.; Baxter, R. H. G.; Miller, S. J.* “X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy.” J. Org. Chem. 2014, 79, 8550 (Featured Article).

Han, S.; Morrison, K.; Hergenrother, P. J.; Movassaghi, M.* “Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (–)-Trigonoliimines.” J. Org. Chem. 2014, 79, 473 (Featured Article, front cover).

Han, S.; Siegel, D. S.; Morrison, K. C.; Hergenrother, P. J.; Movassaghi, M.* “Synthesis and Anticancer Activity of all Known (–)-Agelastatin Alkaloids.” J. Org. Chem. 2013, 78, 11970.

Han, S.; Miller, S. J.* “Asymmetric Catalysis at a Distance: Catalytic, Site-Selective Phosphorylation of Teicoplanin.” J. Am. Chem. Soc. 2013, 135, 12414.

Han, S.; Siegel, D. S.; Movassaghi, M.* “Lithiation and Electrophilic Substitution of Dimethyl Triazones.” Tetrahedron Lett. 2012, 53, 3722.

Han, S.; Movassaghi, M.* “Concise Total Synthesis and Stereochemical Revision of all (–)-Trigonoliimines.” J. Am. Chem. Soc. 2011, 133, 10768 (Most Read Paper on July, 2011 in the J. Am. Chem. Soc).

Movassaghi, M.*; Siegel, S. D.; Han, S. “Total Synthesis of all (–)-Agelastatin Alkaloids.” Chem. Sci. 2010, 1, 561 (Front cover).

Oh, S.; Park, J.; Han, S.; Lee, J.; Roh, E.; Lee, C. J.* “Development of Selective Blockers for Ca2+-ActivatedCl- Channel Using Xenopuslaevis oocytes with an Improved Drug Screening Strategy.” Molecular Brain, 2008, 1, 14.

Chang, S.*; Lee, M.; Jung, D.; Yoo, E.; Cho, S.; Han, S. “Catalytic One-pot Synthesis of Cyclic Amidine by Virtue of Tandem Reactions Involving Intramolecular Hydroamination Under MildCondition.” J. Am. Chem. Soc. 2006, 128, 12366.