Han's Laboratory at KAIST

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Publications

  • Kim, T.; Jeon, S.; Jang, Y.; Gotina, L.; Won, J.; Ju, Y.; Kim, S.; Jang, M.; Won, W.; Park, M.; Pae, A.; Han, S.; Kim, S.;* Lee, C. J.* "Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion" submitted (bioRxiv).

  • Kang, G.; Park, S.; Han, S.* "The Chemistry of High-Oxidation State Securinega Alkaloids" Eur. J. Org. Chem. 2021, in press (YourJOC talents special issue).

  • Kang, G.; Baik, M.-H.;* Han, S.* "Calculation-Assisted Stereochemical Analysis of Securingine A" Bull. Kor. Chem. Soc. 2021, ASAP (BKCS special issue "Chemical Synthesis & Reaction Development").

  • Jeon, S.; Lee, J.; Park, S.; Han, S.* "Total Synthesis of Dimeric Securinega Alkaloids (–)-Flueggenines D and I" Chem. Sci. 2020, 11, 10928 (selected as ChemSci Pick of the Week and inside back cover).

  • Jang, Y.; Han, S.* "Total Synthesis of Cinnamodial-Based Dimer (–)-Capsicodendrin" J. Org. Chem. 2020, 85, 7576. 

  • Kim, G.; Kim. T.; Han, S.* "Total Synthesis of (+)-Pestalofone A and (+)-Iso-A82775C" J. Org. Chem. 2020, 85, 6815.

  • Lee, S.;† Kang, G.;† Chung, G.; Kim, D.; Lee, H.-Y.;* Han, S.* "Biosynthetically Inspired Syntheses of Secu'amamine A and Fluvirosaones A and B" Angew. Chem. Int. Ed. 2020, 59, 6894 (†These authors contributed equally).

  • Seong, S.; Lim, H.; Han, S.* "Synthesis of Types II and III Post-Iboga Alkaloids" Strategies and Tactics in Organic Synthesis; Harmata, M., Ed.; Elsevier; 2019, 14, chapter 2,  pp 35-59.

  • Jo, D.; Han, S.* "Total Synthesis of (–)-FD-838 and (–)-Cephalimysin A" Org. Lett. 2019, 21, 6045. 


  • Lim, H.; Seong, S.; Han, S.* "Syntheses of Post-Iboga Alkaloids" Synthesis 2019, 51, 2737 (Bürgenstock Special Section 2018 Future Stars in Organic Chemistry Issue).

  • Park, J.; Jeon, S.; Kang, G.; Lee, J.; Baik, M.-H.*; Han, S.* "Dimerization Strategies for the Synthesis of High-Order Securinega Alkaloids" J. Org. Chem. 2019, 84, 1398.

  • Seong, S.;† Lim, H.;† Han, S.* "Biosynthetically Inspired Transformation of Iboga to Monomeric Post-Iboga Alkaloids" Chem 2019, 5, 353 (†These authors contributed equally).

  • Hwang, J.;† Kang, T.;† Lee, J.; Choi, B.-S.;* Han, S.* "Design, Synthesis, and Biological Evaluation of C7-Functionalized DMXAA Derivatives as Potential Human-STING Agonists" Org. Biomol. Chem. 2019, 17, 1869. (†These authors contributed equally, New Talent 2018 Issue).

  • Kim, G.; Kim, M. J.; Chung, G.; Lee, H.-Y.;* Han, S.* "(+)-Dimericbiscognienyne A: Total Synthesis and Mechanistic Investigations of the Key Heterodimerization" Org. Lett. 2018, 20, 6886.

  • Jo, D.; Han, S.* "Total Syntheses of Spirocyclic PKS-NRPS-based Fungal Metabolites" Chem. Comm. 2018, 54, 6750 (Emerging Investigators 2018 Issue).

  • Kim, T. T.; Kim, H.; Han, S.* "Academic Research Inspired Design of an Expository Organic Chemistry Lab Course." J. Kor. Chem. Soc. 2018, 62, 99 (front cover).

  • Jeon, S.; Park, J.; Han, S.* "Syntheses of Dimeric Securinega Alkaloids." Synlett 2017, 28, 2353 (Invited Synpacts article).

  • Kang, T.; Jo, D.; Han, S.* "Six-Step Total Synthesis of Azaspirene." J. Org. Chem. 2017, 82, 9335.

  • Jeon, S.; Han, S.* "An Accelerated Intermolecular Rauhut–Currier Reaction Enables the Total Synthesis of (–)-Flueggenine C." J. Am. Chem. Soc. 2017, 139, 6302 (highlighted in Synfacts).

  • Jo, D.; Han, S.* “Biomimetic Total Synthesis of (±)-Berkeleyamide D.”  Org. Chem. Front. 2017,  4, 506.

  • Han, S.; Le, B. V.; Hajare, H. S.; Baxter, R. H. G.; Miller, S. J.* “X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy.”  J. Org. Chem. 2014, 79, 8550 (Featured Article).
  • Han, S.; Morrison, K.; Hergenrother, P. J.; Movassaghi, M.* “Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (–)-Trigonoliimines.” J. Org. Chem. 2014, 79, 473 (Featured Article, front cover).
  • Han, S.; Siegel, D. S.; Morrison, K. C.; Hergenrother, P. J.; Movassaghi, M.* “Synthesis and Anticancer Activity of all Known (–)-Agelastatin Alkaloids.” J. Org. Chem. 2013, 78, 11970. 
  • Han, S.; Miller, S. J.* “Asymmetric Catalysis at a Distance: Catalytic, Site-Selective Phosphorylation of Teicoplanin.” J. Am. Chem. Soc. 2013, 135, 12414.
  • Han, S.; Siegel, D. S.; Movassaghi, M.* “Lithiation and Electrophilic Substitution of Dimethyl Triazones.” Tetrahedron Lett. 2012, 53, 3722.
  • Han, S.; Movassaghi, M.* “Concise Total Synthesis and Stereochemical Revision of all (–)-Trigonoliimines.” J. Am. Chem. Soc. 2011, 133, 10768 (Most Read Paper on July, 2011 in the J. Am. Chem. Soc).
  • Movassaghi, M.*; Siegel, S. D.; Han, S. “Total Synthesis of all (–)-Agelastatin Alkaloids.” Chem. Sci. 2010, 1, 561 (Front cover).
  • Oh, S.; Park, J.; Han, S.; Lee, J.; Roh, E.; Lee, C. J.* “Development of Selective Blockers for Ca2+-ActivatedCl- Channel Using Xenopuslaevis oocytes with an Improved Drug Screening Strategy.” Molecular Brain, 2008, 1, 14.
  • Chang, S.*; Lee, M.; Jung, D.; Yoo, E.; Cho, S.; Han, S. “Catalytic One-pot Synthesis of Cyclic Amidine by Virtue of Tandem Reactions Involving Intramolecular Hydroamination Under MildCondition.” J. Am. Chem. Soc. 2006, 128, 12366.
Copyright (c) 2020. The Han Group, KAIST. All rights reserved.

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