Publications
Heo, S.;† Cha, M.;† Zhung, W.; Kiriwan, S.; Yoon, S.; Kim, J.; Cho, I.; Ye, S.; Kim, W.;* Kim, Y.;* Han, S.* submitted (†These authors contributed equally to this work).
Seo, S. M.; Kim, D.; Kim, T.; Han, S.* "Total Synthesis of (–)-Flueggenine A and (–)-15-epi-Flueggenine D" submitted.
Lee, C.; Kang, G.; Kim, T.; Han, S.* "Total Synthesis of (–)-Elodeoidins A and B" submitted.
Goo. B. S.;† Choi, S. B.;† Cho, K. H.;† Lee, S.; Kim, Y.; Baek, J.; Han, S.; Rhee, Y. M.;* Han, S. W.;* "Controlling the Chemoselectivity of Palladium Nanocatalysts With Halobenzene Surface Ligands for Alkyne Semihydrogenation " submitted (†These authors contributed equally to this work).
Park, S.; Kang, G.; Kim, W.; Jeon, S.; Chung, M. K.; Lee, H.-S.; Yoon, D. K.;* Han, S.* "Synthesis of Securingine B Enables Photoresponsive Materials Design" Chem 2025, ASAP.
Kang, G.; Han, S.* "Biomimetic Synthesis of Fluvirosaone A" Bull. Korean Chem. Soc. 2024, ASAP (Invitation to "BKCS Young Advisory Board Members" special issue).
Kim, S.;† Park, I. W.;† Kim, M; Lee, G. S.; Kim, C. S.;* Han, S.* "Synthesis and Structure Revision of Securingine E" Org. Lett. 2024, 26, 7166 (†These authors contributed equally to this work).
Chen, S.; Babazade, R.; Kim, T.; Han, S.;* Jung, Y.* "A Large-Scale Reaction Dataset of Mechanistic Pathways of Organic Reactions " Sci. Data 2024, 11, 863.
Kim, M.;† Park, S.;† Kang, G.;† Jang, Y. S.;† Kim, K. H.;* Han, S.;* Kim, C. S.* "Natural Product Anticipation via Chemical Synthesis: Discovery of Two New Securinega Alkaloids " iScience 2024, 27, 110495 (†These authors contributed equally to this work).
Lee, S.; Kang, G.;* Han, S.* "Development of an Easy-To-Handle Redox Active Group for Alcohols: Catalytic Transformation of Tertiary Alcohols to Nitriles" Org. Lett. 2024, 26, 5640.
Youn, T.; Kim, T.; Han, S.* "Total Synthesis of (–)-Securingine G " Chem. Commun. 2024, 60, 6391.
Kim, S.; H.-S. Lee.; Han, S.* "Transformation of (allo)securinine to (allo)norsecurinine via a molecular editing strategy" Front. Chem. 2024, 12, 1355636 (Invitation to "Recent Advances in Synthesizing and Utilizing Nitrogen-containing Heterocycles" special issue edited by Prof. Hyun-Joon Ha).
Kang, G.; Han, S.* "Synthesis of Suffranidine B" J. Am. Chem. Soc. 2023, 145, 24493.
Kim, T.; Kim, S.; Chung, G.; Park, K.;* Han, S.* "Re-examining the Stereochemistry of Polycyclic Suffruticosine via TDDFT Calculations, ECD Spectroscopy, and Chemical Synthesis" Org. Chem. Front. 2023, 10, 5123.
Park, S.; Kim, D.; Yang, W.; Han, S.* "Total Synthesis of 4α-Hydroxyallosecurinine and Securingine F, Securinega Alkaloids with a C4-Hydroxyl Handle for Biofunctional Derivatizations" Synlett 2024, 35, 593 (Highlighted in Synform News section).
Kim, J.;† Lee, S.;† Han, S.;* Lee, H.-Y.* "Divergent Synthesis of Conidiogenones B–F and 12β-Hydroxyconidiogenone C " Chem 2023, 9, 1270 (†These authors contributed equally to this work).
Kang, G.; Park, S. Han, S.* "Synthesis of High-Order and High-Oxidation State Securinega Alkaloids" Acc. Chem. Res. 2023, 56, 140.
Han, S.* "“K-Synthesis”: Recent Advancements in Natural Product Synthesis Enabled by Unique Methods and Strategies Development in Korea" Bull. Kor. Chem. Soc. 2023, 44, 172.
Shin, J. S.; Lee, J.; Han, S.;* Lee, H.-Y.* "Gold-Catalyzed Alkyne-Diol Bicycloketalization Enables Enantioselective Divergent Total Syntheses of Attenols" Org. Chem. Front. 2022, 9, 5840.
Park, S.; Kang, G.; Kim, C.; Kim, D.; Han, S.* "Collective Total Synthesis of C4-Oxygenated Securinine-Type Alkaloids via Stereocontrolled Diversifications on the Piperidine Core" Nature Commun. 2022, 13, 5149.
Jang, Y.;† Kim, T. Y.;† Jeon, S.; Lim, H.; Lee, J.; Kim, S.;* Lee, C. J.; * Han, S.* "Synthesis and Structure-Activity Relationship Study of Saponin-Based Membrane Fusion Inhibitors Against SARS-CoV-2" Bioorg. Chem. 2022, 127, 105985 (†These authors contributed equally to this work).
Jee, D. W.; Myung, J.; Little, R. D.;* Han, S.;* Lee, H.-Y.* "Alkylidene Carbene from Silyl Vinyl Iodide Provides Mechanistic Insights on Trimethylenemethane Diyl-Mediated Tandem Cyclizations" Org. Lett. 2022, 24, 4399.
Kang, G; Han, S.* "Synthesis of Dimeric Securinega Alkaloid Flueggeacosine B: From Pd-Catalyzed Cross-Coupling to Cu-Catalyzed Cross-Dehydrogenative Coupling" J. Am. Chem. Soc. 2022, 144, 8932.
Jeon, H; Kang, G.; Kim, M. J.; Shin, J. S.; Han, S.;* Lee, H. -Y.* "On the Erosion of Enantiopurity of Rhodonoids via Their Asymmetric Total Synthesis" Org. Lett. 2022, 24, 2181.
Kim, T. T.;† Lee, C.;† Kim, D.; Lee, H.-S.; Han, S.* "Synthesis and Reactivity of 1-Hydroxyherquline A" Org. Lett. 2022, 24, 1964 (†These authors contributed equally to this work).
Lim, H.;† Seong, S.;† Kim, Y.; Seo, S.; Han, S.* "Biopatterned Reorganization of Alkaloids Enabled by Ring-Opening Functionalization of Tertiary Amines" J. Am. Chem. Soc. 2021, 143, 19966 (†These authors contributed equally to this work).
Kim, T. T.; Lee, C.; Heo, S.; Lee, H.-S.; Han, S.* "Synthesis of Pentacyclic Framework of Herquline A" Chem. Asian. J. 2021, 16, 3382.
Kim, T.; Jeon, S.; Jang, Y.; Gotina, L.; Won, J.; Ju, Y.; Kim, S.; Jang, M.; Won, W.; Park, M.; Pae, A.; Han, S.; Kim, S.;* Lee, C. J.* "Platycodin D, a natural component of Platicodon Grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion" Exp. Mol. Med. 2021, 53, 956.
Kang, G.; Park, S.; Han, S.* "The Chemistry of High-Oxidation State Securinega Alkaloids" Eur. J. Org. Chem. 2021, 2021, 1508 (YourJOC talents special issue).
Kang, G.; Baik, M.-H.;* Han, S.* "Calculation-Assisted Stereochemical Analysis of Securingine A" Bull. Kor. Chem. Soc. 2021, 42, 486 (BKCS special issue "Chemical Synthesis & Reaction Development").
Jeon, S.; Lee, J.; Park, S.; Han, S.* "Total Synthesis of Dimeric Securinega Alkaloids (–)-Flueggenines D and I" Chem. Sci. 2020, 11, 10928 (selected as ChemSci Pick of the Week and inside back cover. Highlighted in Synfacts).
Jang, Y.; Han, S.* "Total Synthesis of Cinnamodial-Based Dimer (–)-Capsicodendrin" J. Org. Chem. 2020, 85, 7576.
Kim, G.; Kim. T.; Han, S.* "Total Synthesis of (+)-Pestalofone A and (+)-Iso-A82775C" J. Org. Chem. 2020, 85, 6815.
Lee, S.;† Kang, G.;† Chung, G.; Kim, D.; Lee, H.-Y.;* Han, S.* "Biosynthetically Inspired Syntheses of Secu'amamine A and Fluvirosaones A and B" Angew. Chem. Int. Ed. 2020, 59, 6894 (†These authors contributed equally to this work).
Seong, S.; Lim, H.; Han, S.* "Synthesis of Types II and III Post-Iboga Alkaloids" Strategies and Tactics in Organic Synthesis; Harmata, M., Ed.; Elsevier; 2019, 14, chapter 2, pp 35-59.
Jo, D.; Han, S.* "Total Synthesis of (–)-FD-838 and (–)-Cephalimysin A" Org. Lett. 2019, 21, 6045.
Lim, H.; Seong, S.; Han, S.* "Syntheses of Post-Iboga Alkaloids" Synthesis 2019, 51, 2737 (Bürgenstock Special Section 2018 Future Stars in Organic Chemistry Issue).
Park, J.; Jeon, S.; Kang, G.; Lee, J.; Baik, M.-H.*; Han, S.* "Dimerization Strategies for the Synthesis of High-Order Securinega Alkaloids" J. Org. Chem. 2019, 84, 1398.
Seong, S.;† Lim, H.;† Han, S.* "Biosynthetically Inspired Transformation of Iboga to Monomeric Post-Iboga Alkaloids" Chem 2019, 5, 353 (†These authors contributed equally to this work).
Hwang, J.;† Kang, T.;† Lee, J.; Choi, B.-S.;* Han, S.* "Design, Synthesis, and Biological Evaluation of C7-Functionalized DMXAA Derivatives as Potential Human-STING Agonists" Org. Biomol. Chem. 2019, 17, 1869. (†These authors contributed equally, New Talent 2018 Issue).
Kim, G.; Kim, M. J.; Chung, G.; Lee, H.-Y.;* Han, S.* "(+)-Dimericbiscognienyne A: Total Synthesis and Mechanistic Investigations of the Key Heterodimerization" Org. Lett. 2018, 20, 6886.
Jo, D.; Han, S.* "Total Syntheses of Spirocyclic PKS-NRPS-based Fungal Metabolites" Chem. Comm. 2018, 54, 6750 (Emerging Investigators 2018 Issue).
Kim, T. T.; Kim, H.; Han, S.* "Academic Research Inspired Design of an Expository Organic Chemistry Lab Course." J. Kor. Chem. Soc. 2018, 62, 99 (front cover).
Jeon, S.; Park, J.; Han, S.* "Syntheses of Dimeric Securinega Alkaloids." Synlett 2017, 28, 2353 (Invited Synpacts article).
Kang, T.; Jo, D.; Han, S.* "Six-Step Total Synthesis of Azaspirene." J. Org. Chem. 2017, 82, 9335.
Jeon, S.; Han, S.* "An Accelerated Intermolecular Rauhut–Currier Reaction Enables the Total Synthesis of (–)-Flueggenine C." J. Am. Chem. Soc. 2017, 139, 6302 (highlighted in Synfacts).
Jo, D.; Han, S.* “Biomimetic Total Synthesis of (±)-Berkeleyamide D.” Org. Chem. Front. 2017, 4, 506.
Han, S.; Le, B. V.; Hajare, H. S.; Baxter, R. H. G.; Miller, S. J.* “X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy.” J. Org. Chem. 2014, 79, 8550 (Featured Article).
Han, S.; Morrison, K.; Hergenrother, P. J.; Movassaghi, M.* “Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (–)-Trigonoliimines.” J. Org. Chem. 2014, 79, 473 (Featured Article, front cover).
Han, S.; Siegel, D. S.; Morrison, K. C.; Hergenrother, P. J.; Movassaghi, M.* “Synthesis and Anticancer Activity of all Known (–)-Agelastatin Alkaloids.” J. Org. Chem. 2013, 78, 11970.
Han, S.; Miller, S. J.* “Asymmetric Catalysis at a Distance: Catalytic, Site-Selective Phosphorylation of Teicoplanin.” J. Am. Chem. Soc. 2013, 135, 12414.
Han, S.; Siegel, D. S.; Movassaghi, M.* “Lithiation and Electrophilic Substitution of Dimethyl Triazones.” Tetrahedron Lett. 2012, 53, 3722.
Han, S.; Movassaghi, M.* “Concise Total Synthesis and Stereochemical Revision of all (–)-Trigonoliimines.” J. Am. Chem. Soc. 2011, 133, 10768 (Most Read Paper on July, 2011 in the J. Am. Chem. Soc).
Movassaghi, M.*; Siegel, S. D.; Han, S. “Total Synthesis of all (–)-Agelastatin Alkaloids.” Chem. Sci. 2010, 1, 561 (Front cover).
Oh, S.; Park, J.; Han, S.; Lee, J.; Roh, E.; Lee, C. J.* “Development of Selective Blockers for Ca2+-ActivatedCl- Channel Using Xenopuslaevis oocytes with an Improved Drug Screening Strategy.” Molecular Brain, 2008, 1, 14.
Chang, S.*; Lee, M.; Jung, D.; Yoo, E.; Cho, S.; Han, S. “Catalytic One-pot Synthesis of Cyclic Amidine by Virtue of Tandem Reactions Involving Intramolecular Hydroamination Under Mild Condition.” J. Am. Chem. Soc. 2006, 128, 12366.